Hereditary spherocytosis in the deer mouse. Its similarity to the human disease.

Hereditary Spherocytosis Unmasked by Human Parvovirus B19 Induced Aplastic Crisis in a Family

Human parvovirus (HPV) B19 induced aplastic crisis in a family leading to the diagnosis of hereditary spherocytosis (HS) is a very rare condition being barely reported in the literature. We herein report a 4-year-old girl, her brother, and their mother who all presented with progressive pallor and jaundice after a febrile illness. The HPV B19 was diagnosed using polymerase chain reaction (PCR) ...

Treatment of hereditary spherocytosis in Peromyscus by radiation and allogeneic bone marrow transplantation.

N INHERITED DISEASE of the bone marrow identical in its pathophysiology to human hereditary spherocytosis has been described in the deer mouse, Peromyscus maniculatus.1 The pathology and hematology of the syndrome have been presented in detail elsewhere.2 In the mouse, as in man, the red cells of affected individuals are spherocytic, show increased osmotic fragility, and have a greatly reduced ...

Hereditary Spherocytosis among Neonates with Jaundice in Bandar Abbas, South Iran

Background: Neonates affected by hereditary spherocytosis may suffer from significant jaundice. This study was conducted on neonates with jaundice hospitalized at the Children’s Hospital in Bandar Abbas, South Iran, to determine the frequency of hereditary spherocytosis among them. Patients and Methods: In this cross-sectional study, 814 neonates with jaundice hospitalized at the Children’s ...

Management of Anesthesia During Splenectomy and Cholecystectomy in a Pregnant Woman With Hereditary Spherocytosis

Hereditary spherocytosis (HS) is a familial hemolytic disorder with intracorpuscular mechanism that characterized by the production of red blood cells with sphere-like shape prone to hemolysis and can lead to hemolytic anemia, splenomegaly, jaundice and gallstones. One of the main reasons for referring these patients to the operating room is splenectomy and cholecystectomy to treat the complica...

Adverse effects of raised environment temperature on the expression of hereditary spherocytosis in deer mice.